simulation of major histocompatibility complex (mhc) structure and peptide loading into an mhc binding pocket with teachers’hands
نویسندگان
چکیده
molecular understanding of three-dimensional (3d) peptide: mhc models require both basic knowledge of computational modeling and skilled visual perception, which are not possessed by all students. the present model aims to simulate mhc molecular structure with the hands and make a profound impression on the students.
منابع مشابه
Simulation of Major Histocompatibility Complex (MHC) Structure and Peptide Loading into an MHC Binding Pocket with Teachers’Hands
Molecular understanding of three-dimensional (3D) peptide: MHC models require both basic knowledge of computational modeling and skilled visual perception, which are not possessed by all students. The present model aims to simulate MHC molecular structure with the hands and make a profound impression on the students.
متن کاملSimulation of Major Histocompatibility Complex (MHC) structure and peptide loading into an MHC binding pocket with teachers'hands.
Molecular understanding of three-dimensional (3D) peptide: MHC models require both basic knowledge of computational modeling and skilled visual perception, which are not possessed by all students. The present model aims to simulate MHC molecular structure with the hands and make a profound impression on the students.
متن کامل'Ovar-Mhc' - ovine major histocompatibility complex: structure and gene polymorphisms.
The major histocompatibility complex (MHC) in sheep, Ovar-Mhc, is poorly characterised, when compared to other domestic animals. However, its basic structure is similar to that of other mammals, comprising class I, II and III regions. Currently, there is evidence for the existence of four class I loci. The class II region is better characterised, with evidence of one DRA, four DRB (one coding a...
متن کاملAn Ontology for Major Histocompatibility Complex (MHC) Alleles and Molecules
We present a formally coherent and consistent multi-species MHC ontology which includes all human MHC alleles and serological groups. The ontology is part of StemNet, a knowledge management system for hematopoietic stem cell transplantation with an integrated semantic search engine. The Owl-encoded MHC ontology contributes to the system in a threefold manner. First, it supports query formulatio...
متن کاملAssembly and function of the major histocompatibility complex (MHC) I peptide-loading complex are conserved across higher vertebrates.
Antigen presentation to cytotoxic T lymphocytes via major histocompatibility complex class I (MHC I) molecules depends on the heterodimeric transporter associated with antigen processing (TAP). For efficient antigen supply to MHC I molecules in the ER, TAP assembles a macromolecular peptide-loading complex (PLC) by recruiting tapasin. In evolution, TAP appeared together with effector cells of a...
متن کاملT cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen
While recent evidence strongly suggests that the third complementarity determining regions (CDR3s) of T cell receptors (TCRs) directly contact antigenic peptides bound to major histocompatibility complex (MHC) molecules, the nature of other TCR contact(s) is less clear. Here we probe the extent to which different antigens can affect this interaction by comparing the responses of T cells bearing...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
reports of biochemistry and molecular biologyجلد ۲، شماره ۱، صفحات ۵۶-۵۸
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023